Police received a call late Monday night about drug activity in a house on Route 94 in Hernshaw.
When they knocked on the door, several people fled by jumping out of a window.
Police arrested six people, including three from Detroit.
They are Hal John Cooper, Dawn Nicole Flourney and Jack Deon Cooper.
Jack Cooper was found in a closet with a pistol.
The owner of the home, Michael Hargis, Bryan Mills of Seth and Chris Holstein of Sylvester were also arrested.
Police found several types of drugs, weapons and a large amount of cash.