Reds vs. Cardinals Predictions & Picks: Odds, Moneyline, Spread - May 22

Monday's game at Great American Ball Park has the St. Louis Cardinals (21-27) taking on the Cincinnati Reds (19-27) at 6:40 PM ET (on May 22). Our computer prediction projects a narrow 4-2 win for the Cardinals, so expect a competitive matchup.

This contest's pitching matchup is set, as the Cardinals will send Jordan Montgomery (2-6) to the mound, while Brandon Williamson will answer the bell for the Reds.

Reds vs. Cardinals Game Info & Odds

• When: Monday, May 22, 2023 at 6:40 PM ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: BSOH
• Live Stream: Watch this game on Fubo!

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Reds vs. Cardinals Score Prediction

Our prediction for this contest is Cardinals 4, Reds 3.

Total Prediction for Reds vs. Cardinals

• Total Prediction: Under 10 runs

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Discover More About This Game

Reds Performance Insights

• The Reds have played as the underdog in nine of their past 10 games and have gone 4-5 in those contests.
• In its last 10 matchups with a total posted by sportsbooks, Cincinnati and its opponents are 5-5-0 when it comes to hitting the over.
• Bookmakers have yet to post a spread in any of the Reds' past 10 games.
• The Reds have won in 12, or 36.4%, of the 33 contests they have been named as odds-on underdogs this year.
• Cincinnati has a mark of 4-7 in contests where sportsbooks favor it by +155 or worse on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Reds have a 39.2% chance of pulling out a win.
• The offense for Cincinnati is the No. 22 offense in MLB, scoring 4.2 runs per game (195 total runs).
• The Reds have pitched to a 5.08 ERA this season, which ranks 28th in baseball.

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