Reds vs. Pirates Predictions & Picks: Odds, Moneyline, Spread - September 22

Friday's contest at Great American Ball Park has the Cincinnati Reds (79-75) squaring off against the Pittsburgh Pirates (72-81) at 6:40 PM ET (on September 22). Our computer prediction projects a narrow 5-3 win for the Reds, so it should be a tight matchup.

This contest's pitching matchup is set, as the Reds will send Andrew Abbott (8-5) to the mound, while Andre Jackson (1-3) will get the nod for the Pirates.

Reds vs. Pirates Game Info & Odds

• When: Friday, September 22, 2023 at 6:40 PM ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: BSOH
• Live Stream: Watch this game on Fubo!

Bet on this matchup with BetMGM Sportsbook and use bonus code "GNPLAY" for special offers!

Reds vs. Pirates Score Prediction

Our prediction for this contest is Reds 5, Pirates 4.

Total Prediction for Reds vs. Pirates

• Total Prediction: Under 9.5 runs

Sportsbook Promo Codes

Explore More About This Game

• Reds Injury Report

• Reds vs Pirates Betting Trends & Stats

• Reds vs Pirates Pitching Matchup

• How to Watch Reds vs Pirates

• Reds vs Pirates Odds

Reds Performance Insights

• The Reds have played as the favorite in three of their past 10 games and have won two of those contests.
• In its last 10 games with a total, Cincinnati and its opponents have combined to hit the over four times.
• Sportsbooks have not set a spread for any of the Reds' last 10 games.
• This season, the Reds have won 20 out of the 36 games, or 55.6%, in which they've been favored.
• This season Cincinnati has won four of its seven games when favored by at least -160 on the moneyline.
• The moneyline for this contest implies a 61.5% chance of a victory for the Reds.
• Cincinnati has scored 720 runs (4.7 per game) this season, which ranks 11th in MLB.
• The Reds have the 23rd-ranked team ERA among all league pitching staffs (4.73).

Put your picks to the test and bet on with BetMGM Sportsbook. Use bonus code "GNPLAY" for special offers!

Reds Schedule